BDBM50118325 1-Benzo[b]thiophen-3-yl-3-[4-(1,2-dihydro-quinolin-2-yl)-piperazin-1-yl]-propan-1-ol::CHEMBL131691

SMILES OC(CCN1CCN(CC1)C1Nc2ccccc2C=C1)c1csc2ccccc12

InChI Key InChIKey=OJOWITMTCTZCJP-UHFFFAOYSA-N

Data  2 KI  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50118325   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Universidad de Navarra

Curated by ChEMBL
LigandPNGBDBM50118325(1-Benzo[b]thiophen-3-yl-3-[4-(1,2-dihydro-quinolin...)
Show SMILES OC(CCN1CCN(CC1)C1Nc2ccccc2C=C1)c1csc2ccccc12
Show InChI InChI=1S/C24H27N3OS/c28-22(20-17-29-23-8-4-2-6-19(20)23)11-12-26-13-15-27(16-14-26)24-10-9-18-5-1-3-7-21(18)25-24/h1-10,17,22,24-25,28H,11-16H2
Affinity DataKi:  9.90nMAssay Description:Binding affinity towards Serotonin transporter (5-HTT) in rat frontal cortex homogenatesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad de Navarra

Curated by ChEMBL
LigandPNGBDBM50118325(1-Benzo[b]thiophen-3-yl-3-[4-(1,2-dihydro-quinolin...)
Show SMILES OC(CCN1CCN(CC1)C1Nc2ccccc2C=C1)c1csc2ccccc12
Show InChI InChI=1S/C24H27N3OS/c28-22(20-17-29-23-8-4-2-6-19(20)23)11-12-26-13-15-27(16-14-26)24-10-9-18-5-1-3-7-21(18)25-24/h1-10,17,22,24-25,28H,11-16H2
Affinity DataKi:  10.2nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenatesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad de Navarra

Curated by ChEMBL
LigandPNGBDBM50118325(1-Benzo[b]thiophen-3-yl-3-[4-(1,2-dihydro-quinolin...)
Show SMILES OC(CCN1CCN(CC1)C1Nc2ccccc2C=C1)c1csc2ccccc12
Show InChI InChI=1S/C24H27N3OS/c28-22(20-17-29-23-8-4-2-6-19(20)23)11-12-26-13-15-27(16-14-26)24-10-9-18-5-1-3-7-21(18)25-24/h1-10,17,22,24-25,28H,11-16H2
Affinity DataIC50: 31.5nMAssay Description:Inhibition of (+)-8-OH-DPAT stimulated [35S]-GTP-gammaS, binding to 5-hydroxytryptamine 1A receptor in hippocampal membranesMore data for this Ligand-Target Pair