BDBM50118470 CHEMBL1218::N-[2-(1,6,7,8-Tetrahydro-2H-3-oxa-as-indacen-8-yl)-ethyl]-propionamide(S)-(-)-22b::RAMELTEON::Rozerem
SMILES CCC(=O)NCC[C@@H]1CCc2ccc3OCCc3c12
InChI Key InChIKey=YLXDSYKOBKBWJQ-LBPRGKRZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50118470
Affinity DataKi: 0.0138nMAssay Description:Binding affinity against human Melatonin receptor type 1A (MT1)More data for this Ligand-Target Pair
Affinity DataKi: 0.0140nMAssay Description:Binding affinity to human MT1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0450nMAssay Description:Binding affinity against human Melatonin receptor type 1B (MT2)More data for this Ligand-Target Pair
Affinity DataKi: 0.112nMAssay Description:Binding affinity to human MT2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibition of human placental Monoamine oxidase A (competitive inhibition was observed)More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair