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BDBM50118481 2-Amino-3-(3-hydroxy-isoxazol-5-yl)-propionic acid::CHEMBL337075

SMILES: N[C@H](Cc1cc(=O)[nH]o1)C(O)=O

InChI Key: InChIKey=PEHXWVXZPICGAV-SCSAIBSYSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50118481   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor


(RAT)
BDBM50118481
PNG
(2-Amino-3-(3-hydroxy-isoxazol-5-yl)-propionic acid...)
Show SMILES N[C@H](Cc1cc(=O)[nH]o1)C(O)=O
Show InChI InChI=1S/C6H8N2O4/c7-4(6(10)11)1-3-2-5(9)8-12-3/h2,4H,1,7H2,(H,8,9)(H,10,11)/t4-/m1/s1
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Article
PubMed
n/an/an/an/a>1.00E+6n/an/an/an/a



The Royal Danish School of Pharmacy

Curated by ChEMBL


Assay Description
Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 1


J Med Chem 45: 4240-5 (2002)


Article DOI: 10.1021/jm020122x
BindingDB Entry DOI: 10.7270/Q28G8K2W
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4 (mGlu4)


(Rattus norvegicus (Rat))
BDBM50118481
PNG
(2-Amino-3-(3-hydroxy-isoxazol-5-yl)-propionic acid...)
Show SMILES N[C@H](Cc1cc(=O)[nH]o1)C(O)=O
Show InChI InChI=1S/C6H8N2O4/c7-4(6(10)11)1-3-2-5(9)8-12-3/h2,4H,1,7H2,(H,8,9)(H,10,11)/t4-/m1/s1
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Article
PubMed
n/an/an/an/a>1.00E+6n/an/an/an/a



The Royal Danish School of Pharmacy

Curated by ChEMBL


Assay Description
Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 4


J Med Chem 45: 4240-5 (2002)


Article DOI: 10.1021/jm020122x
BindingDB Entry DOI: 10.7270/Q28G8K2W
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50118481
PNG
(2-Amino-3-(3-hydroxy-isoxazol-5-yl)-propionic acid...)
Show SMILES N[C@H](Cc1cc(=O)[nH]o1)C(O)=O
Show InChI InChI=1S/C6H8N2O4/c7-4(6(10)11)1-3-2-5(9)8-12-3/h2,4H,1,7H2,(H,8,9)(H,10,11)/t4-/m1/s1
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Article
PubMed
n/an/an/an/a>1.00E+6n/an/an/an/a



The Royal Danish School of Pharmacy

Curated by ChEMBL


Assay Description
Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 2


J Med Chem 45: 4240-5 (2002)


Article DOI: 10.1021/jm020122x
BindingDB Entry DOI: 10.7270/Q28G8K2W
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor


(Rattus norvegicus (Rat))
BDBM50118481
PNG
(2-Amino-3-(3-hydroxy-isoxazol-5-yl)-propionic acid...)
Show SMILES N[C@H](Cc1cc(=O)[nH]o1)C(O)=O
Show InChI InChI=1S/C6H8N2O4/c7-4(6(10)11)1-3-2-5(9)8-12-3/h2,4H,1,7H2,(H,8,9)(H,10,11)/t4-/m1/s1
PDB
MMDB

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B.MOAD
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CHEMBL
PC cid
PC sid
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Article
PubMed
n/an/an/an/a>1.00E+6n/an/an/an/a



The Royal Danish School of Pharmacy

Curated by ChEMBL


Assay Description
Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 5


J Med Chem 45: 4240-5 (2002)


Article DOI: 10.1021/jm020122x
BindingDB Entry DOI: 10.7270/Q28G8K2W
More data for this
Ligand-Target Pair