BDBM50118759 3-(carboxyformamido)-5-(4-methoxyphenyl)thiophene-2-carboxylic acid::5-(4-Methoxy-phenyl)-3-(oxalyl-amino)-thiophene-2-carboxylic acid::CHEMBL336894

SMILES COc1ccc(cc1)-c1cc(NC(=O)C(O)=O)c(s1)C(O)=O

InChI Key InChIKey=FBXLTJIJKDMQMB-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50118759   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118759(3-(carboxyformamido)-5-(4-methoxyphenyl)thiophene-...)
Affinity DataKi:  8.91E+3nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118759(3-(carboxyformamido)-5-(4-methoxyphenyl)thiophene-...)
Affinity DataKi:  8.99E+3nMAssay Description:Binding affinity to PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50118759(3-(carboxyformamido)-5-(4-methoxyphenyl)thiophene-...)
Affinity DataKi:  9.00E+3nMpH: 5.5Assay Description:Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50118759(3-(carboxyformamido)-5-(4-methoxyphenyl)thiophene-...)
Affinity DataKi:  1.50E+5nMpH: 5.5Assay Description:Inhibitory effect against human protein-tyrosine phosphatase alpha (PTPalpha), using p-nitrophenyl phosphate substrate at pH 5.5.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed