BDBM50118943 (2S,3S)-2-amino-3-methyl-1-(pyrrolidin-1-yl)pentan-1-one::CHEMBL503274

SMILES CC[C@H](C)[C@H](N)C(=O)N1CCCC1

InChI Key InChIKey=IMCMJLZQYAUSFW-IUCAKERBSA-N

Data  4 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50118943   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
University Of Antwerp (Uia)

Curated by ChEMBL
LigandPNGBDBM50118943((2S,3S)-2-amino-3-methyl-1-(pyrrolidin-1-yl)pentan...)
Affinity DataKi:  218nMAssay Description:Inhibition of Dipeptidyl Peptidase IVMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
University Of Antwerp (Uia)

Curated by ChEMBL
LigandPNGBDBM50118943((2S,3S)-2-amino-3-methyl-1-(pyrrolidin-1-yl)pentan...)
Affinity DataKi:  410nMAssay Description:In vitro test for inhibitory activity against human dipeptidyl peptidase IV.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
University Of Antwerp (Uia)

Curated by ChEMBL
LigandPNGBDBM50118943((2S,3S)-2-amino-3-methyl-1-(pyrrolidin-1-yl)pentan...)
Affinity DataKi:  440nMAssay Description:In vitro test for inhibitory activity against human dipeptidyl peptidase IV.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
University Of Antwerp (Uia)

Curated by ChEMBL
LigandPNGBDBM50118943((2S,3S)-2-amino-3-methyl-1-(pyrrolidin-1-yl)pentan...)
Affinity DataKi:  2.47E+4nMAssay Description:Inhibition of Dipeptidyl Peptidase II (Quiescent cell proline peptidase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50118943((2S,3S)-2-amino-3-methyl-1-(pyrrolidin-1-yl)pentan...)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of DPP8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
University Of Antwerp (Uia)

Curated by ChEMBL
LigandPNGBDBM50118943((2S,3S)-2-amino-3-methyl-1-(pyrrolidin-1-yl)pentan...)
Affinity DataIC50:  4.00E+3nMAssay Description:In vitro inhibition of human Dipeptidylpeptidase IV.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase IV(Porphyromonas gingivalis)
University Of Warwick

Curated by ChEMBL
LigandPNGBDBM50118943((2S,3S)-2-amino-3-methyl-1-(pyrrolidin-1-yl)pentan...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of Porphyromonas gingivalis N-terminal His-tagged DPP4 expressed in Escherichia coli using Gly-Pro-p-nitroanilide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
University Of Antwerp (Uia)

Curated by ChEMBL
LigandPNGBDBM50118943((2S,3S)-2-amino-3-methyl-1-(pyrrolidin-1-yl)pentan...)
Affinity DataIC50:  1.10E+5nMAssay Description:Inhibition of DPP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
University Of Antwerp (Uia)

Curated by ChEMBL
LigandPNGBDBM50118943((2S,3S)-2-amino-3-methyl-1-(pyrrolidin-1-yl)pentan...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of DPP4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
University Of Antwerp (Uia)

Curated by ChEMBL
LigandPNGBDBM50118943((2S,3S)-2-amino-3-methyl-1-(pyrrolidin-1-yl)pentan...)
Affinity DataIC50:  1.10E+5nMAssay Description:In vitro inhibition of porcine Dipeptidylpeptidase II.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50118943((2S,3S)-2-amino-3-methyl-1-(pyrrolidin-1-yl)pentan...)
Affinity DataIC50:  1.37E+4nMAssay Description:Inhibition of DPP9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed