BDBM501204 US11021511, Compound 4

SMILES Nc1nc2n(cnc2c(=O)[nH]1)C1OC2COP(O)(=O)OC3C4OCC3(COP(O)(=O)OC1C2CO)OC4n1cnc2c(N)ncnc12

InChI Key

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 501204   

TargetStimulator of interferon genes protein [139-379,H232R](Homo sapiens (Human))
Janssen Biotech

US Patent
LigandPNGBDBM501204(US11021511, Compound 4)
Affinity DataIC50: <10nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′→5′)-monoph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetStimulator of interferon genes protein [138-378](Mus musculus (Mouse))
Janssen Biotech

US Patent
LigandPNGBDBM501204(US11021511, Compound 4)
Affinity DataIC50: <2nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′→5′)-monoph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetStimulator of interferon genes protein [139-379,H232R](Homo sapiens (Human))
Janssen Biotech

US Patent
LigandPNGBDBM501204(US11021511, Compound 4)
Affinity DataEC50:  19nMAssay Description:Agonism of the human STING pathway is assessed in THP1-ISG cells (Invivogen, cat #thp-isg) derived from human THP1 monocyte cell line by stable integ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent