BDBM501204 US11021511, Compound 4
SMILES Nc1nc2n(cnc2c(=O)[nH]1)C1OC2COP(O)(=O)OC3C4OCC3(COP(O)(=O)OC1C2CO)OC4n1cnc2c(N)ncnc12
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 501204
TargetStimulator of interferon genes protein [139-379,H232R](Homo sapiens (Human))
Janssen Biotech
US Patent
Janssen Biotech
US Patent
Affinity DataIC50: <10nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′→5′)-monoph...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein [138-378](Mus musculus (Mouse))
Janssen Biotech
US Patent
Janssen Biotech
US Patent
Affinity DataIC50: <2nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′→5′)-monoph...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein [139-379,H232R](Homo sapiens (Human))
Janssen Biotech
US Patent
Janssen Biotech
US Patent
Affinity DataEC50: 19nMAssay Description:Agonism of the human STING pathway is assessed in THP1-ISG cells (Invivogen, cat #thp-isg) derived from human THP1 monocyte cell line by stable integ...More data for this Ligand-Target Pair