BindingDB logo
myBDB logout

BDBM50120525 1-(3-Oxazol-5-yl-1H-indol-6-yl)-3-o-tolyl-urea::CHEMBL116061

SMILES: Cc1ccccc1NC(=O)Nc1ccc2c(c[nH]c2c1)-c1cnco1

InChI Key: InChIKey=VEMWFEAEHKVGKC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50120525   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50120525
PNG
(1-(3-Oxazol-5-yl-1H-indol-6-yl)-3-o-tolyl-urea | C...)
Show SMILES Cc1ccccc1NC(=O)Nc1ccc2c(c[nH]c2c1)-c1cnco1
Show InChI InChI=1S/C19H16N4O2/c1-12-4-2-3-5-16(12)23-19(24)22-13-6-7-14-15(9-21-17(14)8-13)18-10-20-11-25-18/h2-11,21H,1H3,(H2,22,23,24)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 35n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibitory concentration against Inosine-5'-monophosphate dehydrogenase 2 was determined


Bioorg Med Chem Lett 12: 3305-8 (2002)


Article DOI: 10.1016/s0960-894x(02)00748-5
BindingDB Entry DOI: 10.7270/Q2Q81CD6
More data for this
Ligand-Target Pair