BDBM50121025 (E)-1-[2,4-Dihydroxy-5-(3-methyl-but-2-enyl)-phenyl]-3-(3,4-dihydroxy-phenyl)-propenone::CHEMBL115452::broussochalcone::broussochalcone A::med.21724, Compound 177

SMILES [#6]\[#6](-[#6])=[#6]\[#6]-c1cc(-[#6](=O)\[#6]=[#6]\c2ccc(-[#8])c(-[#8])c2)c(-[#8])cc1-[#8]

InChI Key InChIKey=FEALTYYKRMRXTG-QPJJXVBHSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50121025   

TargetMaltase-glucoamylase(Homo sapiens (Human))
Shiv Nadar University

Curated by ChEMBL
LigandPNGBDBM50121025((E)-1-[2,4-Dihydroxy-5-(3-methyl-but-2-enyl)-pheny...)
Affinity DataKi:  5.30E+3nMAssay Description:Non-competitive inhibition of alpha-glucosidase (unknown origin) using p-nitrophenyl-alpha-D glucopyranoside as substrate incubated for 30 mins by Li...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Guru Ghasidas Vishwavidyalaya (A Central University)

Curated by ChEMBL
LigandPNGBDBM50121025((E)-1-[2,4-Dihydroxy-5-(3-methyl-but-2-enyl)-pheny...)
Affinity DataIC50:  2.15E+4nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
University Of Nis

Curated by ChEMBL
LigandPNGBDBM50121025((E)-1-[2,4-Dihydroxy-5-(3-methyl-but-2-enyl)-pheny...)
Affinity DataIC50:  600nMAssay Description:Inhibition of xanthine oxidase (unknown origin) using xanthine as substrate measured at every 1 mins up to 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
University Of Bonn

LigandPNGBDBM50121025((E)-1-[2,4-Dihydroxy-5-(3-methyl-but-2-enyl)-pheny...)
Affinity DataIC50:  4.21E+4nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-glucosidase MAL62(Saccharomyces cerevisiae)TBA
LigandPNGBDBM50121025((E)-1-[2,4-Dihydroxy-5-(3-methyl-but-2-enyl)-pheny...)
Affinity DataIC50:  5.30E+9nMAssay Description:Inhibition of baker's yeast alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Guru Ghasidas Vishwavidyalaya (A Central University)

Curated by ChEMBL
LigandPNGBDBM50121025((E)-1-[2,4-Dihydroxy-5-(3-methyl-but-2-enyl)-pheny...)
Affinity DataIC50:  3.68E+4nMAssay Description:The inhibitory activity of the compound tested against human Protein-tyrosine phosphatase 1B enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1a(Human SARS coronavirus (SARS-CoV))
University Of Bonn

LigandPNGBDBM50121025((E)-1-[2,4-Dihydroxy-5-(3-methyl-but-2-enyl)-pheny...)
Affinity DataIC50:  9.20E+3nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed