BDBM50121062 9,9,9-TRIFLUORO-8-OXO-N-PHENYLNONANAMIDE::9,9,9-Trifluoro-8-oxo-nonanoic acid phenylamide::CHEMBL113537
SMILES FC(F)(F)C(=O)CCCCCCC(=O)Nc1ccccc1
InChI Key InChIKey=KRCXZGYVOZSCSF-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50121062
Affinity DataIC50: 6.70E+3nMAssay Description:In vitro inhibitory activity against human histone deacetylase (HDAC) using HeLa nuclear extractMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of HDAC8 assessed as substrate deacetylation using N-acetyl-L-Arg-LHis-L-Lys(epsilon-acetyl)-L-Lys(epsilon-acetyl)-coumarin as substrate p...More data for this Ligand-Target Pair
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of human recombinant HDAC1 using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 30 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of human histone deacetylase (mixture of HDAC1 and HDAC2) prepared from K562 erythroleukemia cells.More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human recombinant HDAC2 using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 30 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
TargetAcetylpolyamine amidohydrolase(Mycoplana ramosa (Gram-negative bacterium))
Drexel University
Curated by ChEMBL
Drexel University
Curated by ChEMBL
Affinity DataIC50: 1.10E+5nMAssay Description:Inhibition of Mycoplana ramosa acetylpolyamine amidohydrolase assessed as substrate deacetylation using L-Lys(epsilon-acetyl)-coumarin as substrate p...More data for this Ligand-Target Pair