BDBM50121062 9,9,9-TRIFLUORO-8-OXO-N-PHENYLNONANAMIDE::9,9,9-Trifluoro-8-oxo-nonanoic acid phenylamide::CHEMBL113537

SMILES FC(F)(F)C(=O)CCCCCCC(=O)Nc1ccccc1

InChI Key InChIKey=KRCXZGYVOZSCSF-UHFFFAOYSA-N

Data  6 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50121062   

TargetHistone deacetylase(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50121062(9,9,9-TRIFLUORO-8-OXO-N-PHENYLNONANAMIDE | 9,9,9-T...)
Affinity DataIC50:  6.70E+3nMAssay Description:In vitro inhibitory activity against human histone deacetylase (HDAC) using HeLa nuclear extractMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50121062(9,9,9-TRIFLUORO-8-OXO-N-PHENYLNONANAMIDE | 9,9,9-T...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of HDAC8 assessed as substrate deacetylation using N-acetyl-L-Arg-LHis-L-Lys(epsilon-acetyl)-L-Lys(epsilon-acetyl)-coumarin as substrate p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Csir-National Chemical Laboratory

Curated by ChEMBL
LigandPNGBDBM50121062(9,9,9-TRIFLUORO-8-OXO-N-PHENYLNONANAMIDE | 9,9,9-T...)
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibition of human recombinant HDAC1 using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 30 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50121062(9,9,9-TRIFLUORO-8-OXO-N-PHENYLNONANAMIDE | 9,9,9-T...)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of human histone deacetylase (mixture of HDAC1 and HDAC2) prepared from K562 erythroleukemia cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Csir-National Chemical Laboratory

Curated by ChEMBL
LigandPNGBDBM50121062(9,9,9-TRIFLUORO-8-OXO-N-PHENYLNONANAMIDE | 9,9,9-T...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human recombinant HDAC2 using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 30 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylpolyamine amidohydrolase(Mycoplana ramosa (Gram-negative bacterium))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50121062(9,9,9-TRIFLUORO-8-OXO-N-PHENYLNONANAMIDE | 9,9,9-T...)
Affinity DataIC50:  1.10E+5nMAssay Description:Inhibition of Mycoplana ramosa acetylpolyamine amidohydrolase assessed as substrate deacetylation using L-Lys(epsilon-acetyl)-coumarin as substrate p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed