BindingDB logo
myBDB logout

BDBM50121946 2-[2-(4'-Methoxy-biphenyl-4-sulfonyl)-ethoxy]-naphthalene-1-carboxylic acid hydroxyamide::CHEMBL348688

SMILES: COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)CCOc1ccc2ccccc2c1C(=O)NO

InChI Key: InChIKey=QFUASBJNVCIDLY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50121946   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Stromelysin-1


(Homo sapiens (Human))
BDBM50121946
PNG
(2-[2-(4'-Methoxy-biphenyl-4-sulfonyl)-ethoxy]-naph...)
Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)CCOc1ccc2ccccc2c1C(=O)NO
Show InChI InChI=1S/C26H23NO6S/c1-32-21-11-6-18(7-12-21)19-8-13-22(14-9-19)34(30,31)17-16-33-24-15-10-20-4-2-3-5-23(20)25(24)26(28)27-29/h2-15,29H,16-17H2,1H3,(H,27,28)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 460n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of Stromelysin (MMP-3)


J Med Chem 45: 5628-39 (2002)


Article DOI: 10.1021/jm020160g
BindingDB Entry DOI: 10.7270/Q20C4V3M
More data for this
Ligand-Target Pair