BDBM50123252 (S)-2-Benzenesulfonylamino-3-{[5-(2-guanidino-phenyl)-thiophene-2-carbonyl]-amino}-propionic acid; TFA::CHEMBL423214

SMILES [#7]\[#6](-[#7])=[#7]\c1ccccc1-c1ccc(s1)-[#6](=O)-[#7]-[#6]-[#6@H](-[#7]S(=O)(=O)c1ccccc1)-[#6](-[#8])=O

InChI Key InChIKey=LOZUMZUMWUTBLC-INIZCTEOSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50123252   

TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123252((S)-2-Benzenesulfonylamino-3-{[5-(2-guanidino-phen...)
Affinity DataIC50:  5.33E+3nMAssay Description:Inhibition of vitronectin binding to HT-29 cells expressing integrin alphaV-beta5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123252((S)-2-Benzenesulfonylamino-3-{[5-(2-guanidino-phen...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of fibrinogen binding to integrin alphaIIb-beta3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123252((S)-2-Benzenesulfonylamino-3-{[5-(2-guanidino-phen...)
Affinity DataIC50:  0.25nMAssay Description:Inhibition of fibrinogen binding to K562 cells expressing integrin alpha5-beta1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed