BDBM50124576 CHEMBL3623736

SMILES OC(=O)c1cccc(Nc2cccc(c2)S(F)(F)(F)(F)F)c1

InChI Key InChIKey=FFUYABNKRZIFBU-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50124576   

TargetAcid-sensing ion channel 5(Rattus norvegicus)
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50124576(CHEMBL3623736)
Affinity DataEC50:  2.90E+6nMAssay Description:Binding affinity to rat bile acid-sensitive ion channel expressed in xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50124576(CHEMBL3623736)
Affinity DataIC50:  86nMAssay Description:Inhibition of recombinant AKR1C3 (unknown origin) using S-tetralol as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50124576(CHEMBL3623736)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of COX2 (unknown origin) using arachidonic acid substrate by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50124576(CHEMBL3623736)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of COX1 (unknown origin) using arachidonic acid substrate by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50124576(CHEMBL3623736)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of recombinant AKR1C2 (unknown origin) using S-tetralol as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed