BDBM50124923 CHEMBL162080::N-(3,5-Dimethyl-benzyl)-4-trifluoromethyl-benzamidine
SMILES Cc1cc(C)cc(CN=C(N)c2ccc(cc2)C(F)(F)F)c1
InChI Key InChIKey=MEBWTXIADKMHNS-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50124923
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 3.90nMAssay Description:Displacement of NMDA receptor-specific [3H]-ifenprodil binding to recombinant human NMDA receptor, NR2B subtype expressed in L cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 8.70nMAssay Description:Inhibition of the response to NMDA glutamate/glycine receptor NR2B subtype was determined using FLIPR assayMore data for this Ligand-Target Pair