BDBM50125028 CHEMBL3623791

SMILES [H][C@@]12CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@]1([H])CSSC[C@]([H])(NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)CNC(=O)[C@H](CC(N)=O)NC2=O)C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N2CCC[C@@]2([H])C(=O)N2CCC[C@@]2([H])C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N1

InChI Key InChIKey=AOMZQHHLSHFCGW-LQFZIJPOSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50125028   

TargetKallikrein-14(Homo sapiens (Human))
Queensland University Of Technology

Curated by ChEMBL
LigandPNGBDBM50125028(CHEMBL3623791)
Affinity DataKi:  7nMAssay Description:Inhibition of KLK14 (unknown origin) expressed in Sf9 cells using Ac-YANR-pNA substrate by spectrophotometry methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-4(Homo sapiens (Human))
Queensland University Of Technology

Curated by ChEMBL
LigandPNGBDBM50125028(CHEMBL3623791)
Affinity DataKi:  20nMAssay Description:Inhibition of KLK4 (unknown origin) expressed in Sf9 cells using FVQRpNA substrate by spectrophotometry methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
Queensland University Of Technology

Curated by ChEMBL
LigandPNGBDBM50125028(CHEMBL3623791)
Affinity DataKi:  3.20E+3nMAssay Description:Inhibition of beta-trypsin (unknown origin) using Bz-FVRpNA substrate by spectrophotometry methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Queensland University Of Technology

Curated by ChEMBL
LigandPNGBDBM50125028(CHEMBL3623791)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of KLK5 (unknown origin) expressed in Pichia pastoris X33 using Ac-YRSR-pNA by spectrophotometry methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed