BDBM50125038 2-[(S)-3-(3-Guanidino-propyl)-2-oxo-piperazin-1-yl]-N-[(S)-4-guanidino-1-(thiazole-2-carbonyl)-butyl]-acetamide::CHEMBL163407::N-((S)-5-guanidino-1-oxo-1-(thiazol-2-yl)pentan-2-yl)-2-((S)-3-(3-guanidinopropyl)-2-oxopiperazin-1-yl)acetamide

SMILES NC(=N)NCCC[C@H](NC(=O)CN1CCN[C@@H](CCCNC(N)=N)C1=O)C(=O)c1nccs1

InChI Key InChIKey=AWIQGIMATAEJMQ-STQMWFEESA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50125038   

TargetProthrombin(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50125038(2-[(S)-3-(3-Guanidino-propyl)-2-oxo-piperazin-1-yl...)
Affinity DataIC50:  1.20E+4nMAssay Description:In vitro inhibitory activity against serine protease thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125038(2-[(S)-3-(3-Guanidino-propyl)-2-oxo-piperazin-1-yl...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50125038(2-[(S)-3-(3-Guanidino-propyl)-2-oxo-piperazin-1-yl...)
Affinity DataIC50:  1.50E+5nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50125038(2-[(S)-3-(3-Guanidino-propyl)-2-oxo-piperazin-1-yl...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibitory activity against factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed