BDBM50126442 CHEMBL285916::N*1*-[7-(3-Chloro-phenyl)-[1,6]naphthyridin-5-yl]-propane-1,3-diamine::N1-(7-(3-chlorophenyl)-1,6-naphthyridin-5-yl)propane-1,3-diamine

SMILES NCCCNc1nc(cc2ncccc12)-c1cccc(Cl)c1

InChI Key InChIKey=GOYXCTUAUOUVCG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50126442   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126442(CHEMBL285916 | N*1*-[7-(3-Chloro-phenyl)-[1,6]naph...)
Affinity DataIC50:  260nMAssay Description:Inhibitory activity against spleen tyrosine kinase (SYK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126442(CHEMBL285916 | N*1*-[7-(3-Chloro-phenyl)-[1,6]naph...)
Affinity DataIC50:  260nMAssay Description:Inhibition of SYKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126442(CHEMBL285916 | N*1*-[7-(3-Chloro-phenyl)-[1,6]naph...)
Affinity DataIC50:  260nMAssay Description:Inhibition of recombinant Syk (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed