BDBM50126730 2-(2,6-Dichloro-phenylamino)-6-(2-hydroxy-ethyl)-1,7-dimethyl-1,8-dihydro-imidazo[4,5-h]isoquinolin-9-one::CHEMBL27079

SMILES Cc1[nH]c(=O)c2c3n(C)c(Nc4c(Cl)cccc4Cl)nc3ccc2c1CCO

InChI Key InChIKey=DCVKALMAVBGUEW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50126730   

TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126730(2-(2,6-Dichloro-phenylamino)-6-(2-hydroxy-ethyl)-1...)
Affinity DataIC50:  27nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed