BDBM50126756 2-(2,6-Dichloro-phenylamino)-4-(2,6-difluoro-pyridin-3-yl)-1,6,7-trimethyl-1,8-dihydro-imidazo[4,5-h]isoquinolin-9-one::CHEMBL26625

SMILES Cc1[nH]c(=O)c2c3n(C)c(Nc4c(Cl)cccc4Cl)nc3c(cc2c1C)-c1ccc(F)nc1F

InChI Key InChIKey=IJQMOGYNJJLTLT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50126756   

TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126756(2-(2,6-Dichloro-phenylamino)-4-(2,6-difluoro-pyrid...)
Affinity DataIC50:  50nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed