BDBM50127388 3-(4-Isopropenyl-phenyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::CHEMBL51154

SMILES COC(=O)C1C2CC[C@H](C[C@@H]1c1ccc(cc1)C(C)=C)N2

InChI Key InChIKey=FIISMIHWBCMEDD-NUWOQIAWSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50127388   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50127388(3-(4-Isopropenyl-phenyl)-8-aza-bicyclo[3.2.1]octan...)
Affinity DataKi:  0.0550nMAssay Description:Inhibition of [3H]paroxetine binding at serotonin transporter was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50127388(3-(4-Isopropenyl-phenyl)-8-aza-bicyclo[3.2.1]octan...)
Affinity DataKi:  87nMAssay Description:Inhibition of [3H]nisoxetine binding at norepinephrine transporter was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50127388(3-(4-Isopropenyl-phenyl)-8-aza-bicyclo[3.2.1]octan...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of [3H]paroxetine binding at serotonin transporter was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50127388(3-(4-Isopropenyl-phenyl)-8-aza-bicyclo[3.2.1]octan...)
Affinity DataIC50:  144nMAssay Description:Inhibition of [3H]nisoxetine binding at norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50127388(3-(4-Isopropenyl-phenyl)-8-aza-bicyclo[3.2.1]octan...)
Affinity DataIC50:  23nMAssay Description:Inhibition of [3H]WIN-35428 binding at dopamine transporter was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed