BDBM50128072 (4-{2-[(Allyl-cyclopropyl-amino)-methyl]-cyclopropylmethoxy}-phenyl)-(4-bromo-phenyl)-methanone::CHEMBL293005::N-allyl-N-(((1S,2S)-2-((4-(4-bromobenzoyl)phenoxy)methyl)cyclopropyl)methyl)cyclopropanaminium::{4-[((1S,2S)-2-{[ALLYL(CYCLOPROPYL)AMINO]METHYL}CYCLOPROPYL)METHOXY]PHENYL}(4-BROMOPHENYL)METHANONE

SMILES Brc1ccc(cc1)C(=O)c1ccc(OC[C@H]2C[C@@H]2CN(CC=C)C2CC2)cc1

InChI Key InChIKey=ICPGWJRDLWZVKA-WOJBJXKFSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50128072   

TargetSqualene--hopene cyclase(Alicyclobacillus acidocaldarius)
Albert-Ludwigs-University Of Freiburg

Curated by ChEMBL
LigandPNGBDBM50128072((4-{2-[(Allyl-cyclopropyl-amino)-methyl]-cycloprop...)
Affinity DataIC50:  59nMAssay Description:Inhibitory activity against squalene hopene cyclase from Alicyclobacillus acidocaldariusMore data for this Ligand-Target Pair
TargetLanosterol synthase(Homo sapiens (Human))
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128072((4-{2-[(Allyl-cyclopropyl-amino)-methyl]-cycloprop...)
Affinity DataIC50:  6.46nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128072((4-{2-[(Allyl-cyclopropyl-amino)-methyl]-cycloprop...)
Affinity DataIC50:  224nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128072((4-{2-[(Allyl-cyclopropyl-amino)-methyl]-cycloprop...)
Affinity DataIC50:  223nMAssay Description:Inhibitory activity against Oxidosqualene-lanosterol cyclase from human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed