BDBM50129156 (Z)-2-(9-fluoro-2,2,4-trimethyl-1,2-dihydrochromeno[3,4-f]quinolin-5-ylidene)acetonitrile::CHEMBL62731::[9-Fluoro-2,2,4-trimethyl-1,2-dihydro-6-oxa-1-aza-chrysen-(5Z)-ylidene]-acetonitrile

SMILES CC1=CC(C)(C)Nc2ccc3-c4cc(F)ccc4O\C(=C/C#N)c3c12

InChI Key InChIKey=WZHDIERNMYGFAD-LSCVHKIXSA-N

Data  2 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50129156   

TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50129156((Z)-2-(9-fluoro-2,2,4-trimethyl-1,2-dihydrochromen...)
Affinity DataKi:  45nMAssay Description:Inhibitory concentration for antagonistic activity towards human progesterone receptor (hPR) using the cotransfection assay in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50129156((Z)-2-(9-fluoro-2,2,4-trimethyl-1,2-dihydrochromen...)
Affinity DataKi:  45nMAssay Description:Displacement of [3H]progesterone from Progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50129156((Z)-2-(9-fluoro-2,2,4-trimethyl-1,2-dihydrochromen...)
Affinity DataIC50:  65nMAssay Description:Inhibitory concentration for antagonistic activity towards human progesterone receptor (hPR) using the cotransfection assay in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50129156((Z)-2-(9-fluoro-2,2,4-trimethyl-1,2-dihydrochromen...)
Affinity DataEC50:  2.70E+3nMAssay Description:Effective concentration for agonist activity towards human progesterone receptor (hPR) using the cotransfection assay in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed