BDBM50129830 CHEMBL3628798

SMILES Brc1cccc(NC(=O)Nc2ccc(Nc3ncnc4sccc34)cc2)c1

InChI Key InChIKey=BGHFCXDUPAVIJR-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50129830   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50129830(CHEMBL3628798)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human EGFR after 1 hr using [gamma-32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50129830(CHEMBL3628798)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of VEGFR1 (unknown origin) by radiometric protein kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50129830(CHEMBL3628798)
Affinity DataIC50:  1.98E+3nMAssay Description:Inhibition of VEGFR3 (unknown origin) by radiometric protein kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50129830(CHEMBL3628798)
Affinity DataIC50:  2.12E+3nMAssay Description:Inhibition of PDGFR-beta (unknown origin) by radiometric protein kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50129830(CHEMBL3628798)
Affinity DataIC50:  1.16E+3nMAssay Description:Inhibition of human recombinant VEGFR-2 after 1 hr using [gamma-32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50129830(CHEMBL3628798)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Src (unknown origin) by radiometric protein kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50129830(CHEMBL3628798)
Affinity DataIC50:  4.02E+3nMAssay Description:Inhibition of Raf (unknown origin) by radiometric protein kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50129830(CHEMBL3628798)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of c-MET (unknown origin) by radiometric protein kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50129830(CHEMBL3628798)
Affinity DataIC50:  1nMAssay Description:Inhibition of c-Kit (unknown origin) by radiometric protein kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed