BDBM50130014 (R)-2-Acetylamino-N-(4-{acetyl-[2-(1H-indol-3-yl)-ethyl]-amino}-cyclohexyl)-N-(4-guanidino-butyl)-3-phenyl-propionamide::1N-[4-amino(imino)methylaminobutyl]-1N-{4-[2-(1H-3-indolyl)ethyl(methyl)carboxamido]cyclohexyl}-2-methylcarboxamido-3-phenyl-(2R)-propanamide::CHEMBL309807

SMILES CC(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCCNC(N)=N)C1CCC(CC1)N(CCc1c[nH]c2ccccc12)C(C)=O

InChI Key InChIKey=WFOFJUYRBUEJBI-ARDYHYPTSA-N

Data  7 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50130014   

TargetMelanocortin receptor 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50130014((R)-2-Acetylamino-N-(4-{acetyl-[2-(1H-indol-3-yl)-...)
Affinity DataIC50:  7.70nMAssay Description:Binding affinity towards human melanocortin 4 receptor (hMC4R) using [125I]NDP-alpha-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50130014((R)-2-Acetylamino-N-(4-{acetyl-[2-(1H-indol-3-yl)-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity towards mouse Melanocortin 1 receptor (mMC1R) using [125I]NDP-alpha-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50130014((R)-2-Acetylamino-N-(4-{acetyl-[2-(1H-indol-3-yl)-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity towards human melanocortin 3 receptor (hMC3R) using [125I]NDP-alpha-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50130014((R)-2-Acetylamino-N-(4-{acetyl-[2-(1H-indol-3-yl)-...)
Affinity DataIC50:  3.50E+3nMAssay Description:Intracellular levels of cAMP in HEK 293 cells expressing human melanocortin 4 receptor (hMC4R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50130014((R)-2-Acetylamino-N-(4-{acetyl-[2-(1H-indol-3-yl)-...)
Affinity DataIC50:  280nMAssay Description:Binding affinity towards human melanocortin 3 receptor (hMC3R) using [125I]NDP-alpha-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50130014((R)-2-Acetylamino-N-(4-{acetyl-[2-(1H-indol-3-yl)-...)
Affinity DataEC50:  680nMAssay Description:Intracellular levels of cAMP in HEK 293 cells expressing human melanocortin 4 receptor (hMC4R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50130014((R)-2-Acetylamino-N-(4-{acetyl-[2-(1H-indol-3-yl)-...)
Affinity DataEC50:  680nMAssay Description:Intracellular levels of cAMP in HEK 293 cells expressing human melanocortin 4 receptor (hMC4R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50130014((R)-2-Acetylamino-N-(4-{acetyl-[2-(1H-indol-3-yl)-...)
Affinity DataIC50:  51nMAssay Description:Binding affinity towards mouse Melanocortin 1 receptor (mMC1R) using [125I]NDP-alpha-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50130014((R)-2-Acetylamino-N-(4-{acetyl-[2-(1H-indol-3-yl)-...)
Affinity DataIC50:  3.50E+3nMAssay Description:Intracellular levels of cAMP in HEK 293 cells expressing human melanocortin 4 receptor (hMC4R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed