BDBM50130273 2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl)ethanol::2-chloro-10-(3-(4-(2-hydroxyethyl)piperazin-1-yl)propyl)phenothiazine::2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethanol::4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol::4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperazineethanol::CHEMBL567::Chlorpiprazine::PERPHENAZINE::Perfenazine::Perphenazin::Trilafon::gamma-(4-(beta-hydroxyethyl)piperazin-1-yl)propyl-2-chlorophenothiazine

SMILES OCCN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc23)CC1

InChI Key InChIKey=RGCVKNLCSQQDEP-UHFFFAOYSA-N

Data  44 KI  23 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 67 hits for monomerid = 50130273   

TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  0.130nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  0.160nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  0.630nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  0.950nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  1.30nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  1.40nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  1.40nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  1.40nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  2.51nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  5.55nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  5.60nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  8.33nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  10nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  10nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  10nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  13nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(RAT)
Friedrich-Schiller-University Jena

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  15.8nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  17nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  17nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(RAT)
Friedrich-Schiller-University Jena

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  17nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
TBA

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  21nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  23nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  23nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  23nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  24nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  25.1nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Schering-Plough

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  29.9nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
TBA

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  42nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Schering-Plough

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  44nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  50.1nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  85.2nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  105nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  132nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  132nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  421nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  500nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  510nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  811nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  1.49E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  1.50E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  1.85E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A/1B/1D/2C(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataKi:  3.57E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataIC50: >1.70E+4nMAssay Description:Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetUbiquitin-conjugating enzyme E2 N(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataIC50:  1.34E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-related protein A1(Mus musculus (Mouse))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataIC50: >2.00E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetUbiquitin-conjugating enzyme E2 N(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataIC50:  1.62E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCytochrome P450 2J2(Homo sapiens (Human))
Tongji University

Curated by ChEMBL
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataIC50:  1.06E+4nMAssay Description:Inhibition of human recombinant CYP2J2 assessed as reduction in astemizole O-demethylation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Tongji University

Curated by ChEMBL
LigandPNGBDBM50130273(2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1...)
Affinity DataIC50:  120nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using bufuralol substrate by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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