BDBM50130426 CHEMBL105261::N-[3-(1-Methyl-piperidin-4-yl)-1H-pyrrolo[3,2-b]pyridin-5-yl]-propionamide

SMILES CCC(=O)Nc1ccc2[nH]cc(C3CCN(C)CC3)c2n1

InChI Key InChIKey=ORJIHHLJBCQRBS-UHFFFAOYSA-N

Data  18 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50130426   

Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50130426(CHEMBL105261 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Affinity DataKi:  5.5nMAssay Description:Binding affinity to 5-HT1F (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50130426(CHEMBL105261 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Affinity DataKi:  5.5nMAssay Description:In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50130426(CHEMBL105261 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Affinity DataKi: >300nMAssay Description:Binding affinity to 5-HT5A receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50130426(CHEMBL105261 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Affinity DataKi: >300nMAssay Description:Binding affinity to 5-HT1D (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50130426(CHEMBL105261 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Affinity DataKi: >300nMAssay Description:Binding affinity to 5-HT1B (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50130426(CHEMBL105261 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Affinity DataKi: >300nMAssay Description:Binding affinity to 5-HT2B (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50130426(CHEMBL105261 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Affinity DataKi: >300nMAssay Description:Binding affinity to 5-HT1A (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50130426(CHEMBL105261 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Affinity DataKi: >300nMAssay Description:Binding affinity to 5-HT2C (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50130426(CHEMBL105261 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Affinity DataKi: >300nMAssay Description:Binding affinity to 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130426(CHEMBL105261 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Affinity DataKi:  310nMAssay Description:In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 2C recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50130426(CHEMBL105261 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Affinity DataKi:  720nMAssay Description:In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1B recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50130426(CHEMBL105261 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Affinity DataKi:  730nMAssay Description:In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1D recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1E(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130426(CHEMBL105261 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Affinity DataKi:  770nMAssay Description:In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1E recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50130426(CHEMBL105261 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Affinity DataKi:  1.00E+3nMAssay Description:In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1A recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130426(CHEMBL105261 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Affinity DataKi:  1.12E+3nMAssay Description:In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130426(CHEMBL105261 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Affinity DataKi:  2.40E+3nMAssay Description:In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130426(CHEMBL105261 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Affinity DataKi:  3.40E+3nMAssay Description:In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 2A recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50130426(CHEMBL105261 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 2B recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50130426(CHEMBL105261 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)
Affinity DataEC50:  32nMAssay Description:In vitro effective concentration for stimulation of [35S]-GTP-gammaS, binding in mouse LM(tk-)cells expressing the human 5-hydroxytryptamine 1F recep...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed