BDBM50131263 CHEMBL3634755::US9260425, 264
SMILES Cn1cc(cn1)-c1cc2c(n[nH]c2cn1)-c1cccc(O[C@@H]2CCCNC2)n1
InChI Key InChIKey=XJYVGYJMUZECDN-CQSZACIVSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50131263
Affinity DataKi: 0.160nMAssay Description:Inhibition of Pim3 (unknown origin) using 5FAM-ARKRRRHPSGPPTA as substrate after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.270nMpH: 7.2Assay Description:PIM-1, PIM-2, and PIM-3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J....More data for this Ligand-Target Pair
Affinity DataKi: 0.270nMAssay Description:Inhibition of Pim1 (unknown origin) using 5FAM-ARKRRRHPSGPPTA as substrate after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 6.20nMAssay Description:Inhibition of Pim2 (unknown origin) using 5FAM-ARKRRRHPSGPPTA as substrate after 90 minsMore data for this Ligand-Target Pair