BDBM50132208 4-(6-Amino-7-ethylamino-quinazolin-4-yl)-piperazine-1-carbothioic acid benzylamide::CHEMBL100542

SMILES CCNc1cc2ncnc(N3CCN(CC3)C(=S)NCc3ccccc3)c2cc1N

InChI Key InChIKey=GPAFALHWHLKNJH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50132208   

TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50132208(4-(6-Amino-7-ethylamino-quinazolin-4-yl)-piperazin...)
Affinity DataIC50:  1.44E+3nMAssay Description:Inhibition of platelet-derived growth factor receptor beta phosphorylation was measured in intact cells using a two-site enzyme linked immunosorbent ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50132208(4-(6-Amino-7-ethylamino-quinazolin-4-yl)-piperazin...)
Affinity DataIC50:  1.44E+3nMAssay Description:Inhibitory concentration against platelet-derived growth factor receptor beta phosphorylation in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed