BDBM50132437 3-((1-(3-hydroxypropyl)-5-methoxy-1H-indol-3-yl)methylene)-2-oxoindoline-5-sulfonamide::3-[1-[1-(3-Hydroxy-propyl)-5-methoxy-1H-indol-3-yl]-meth-(Z)-ylidene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid amide::CHEMBL107061
SMILES COc1ccc2n(CCCO)cc(\C=C3/C(=O)Nc4ccc(cc34)S(N)(=O)=O)c2c1
InChI Key InChIKey=UCMHGBCESZOZPQ-NVMNQCDNSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50132437
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant Syk (unknown origin)More data for this Ligand-Target Pair
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
Aventis Pharmaceuticals
Curated by ChEMBL
Aventis Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Effect on IgE/Fcepsilon RI triggered rat basophil cell (RBL-2H3) degranulation assessed by measuring the amount of 5-HT releaseMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of SYK in rat RBL2H3 cells assessed as reduction in DNP-BSA-stimulated Fcepsilon receptor 1-mediated 5-HT releaseMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibitory activity against human Syk protein tyrosine kinase expressed in yeast Klyveromyces lactisMore data for this Ligand-Target Pair