BDBM50132556 (S)-1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-carboxylic acid (R)-1-(3-carboxymethoxy-phenyl)-3-(3,4-dimethoxy-phenyl)-propyl ester::CHEMBL321022

SMILES CCC(C)(C)C(=O)C(=O)N1CCCC[C@H]1C(=O)O[C@H](CCc1ccc(OC)c(OC)c1)c1cccc(OCC(O)=O)c1

InChI Key InChIKey=CKUAMXWZIHXZJC-LOSJGSFVSA-N

Data  1 KI  7 IC50

PDB links: 2 PDB IDs match this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50132556   

TargetPeptidyl-prolyl cis-trans isomerase FKBP5(Homo sapiens (Human))
Max Institute Of Psychiatry

Curated by ChEMBL
LigandPNGBDBM50132556((S)-1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-...)
Affinity DataKi:  2.70E+3nMAssay Description:Binding affinity to human FKBP51 by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase FKBP5(Homo sapiens (Human))
Max Institute Of Psychiatry

Curated by ChEMBL
LigandPNGBDBM50132556((S)-1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-...)
Affinity DataIC50:  6.30E+3nMAssay Description:Binding affinity to FKBP51 FK1 domain by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase FKBP4(Homo sapiens (Human))
Max Planck Institute Of Psychiatry

Curated by ChEMBL
LigandPNGBDBM50132556((S)-1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-...)
Affinity DataIC50:  1.05E+4nMAssay Description:Binding affinity to FKBP52 FK1 domain by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Max Planck Institute Of Psychiatry

Curated by ChEMBL
LigandPNGBDBM50132556((S)-1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-...)
Affinity DataIC50:  114nMAssay Description:Binding affinity to FKBP12 by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Max Planck Institute Of Psychiatry

Curated by ChEMBL
LigandPNGBDBM50132556((S)-1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-...)
Affinity DataIC50:  170nMAssay Description:Binding affinity to FKBP12 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP5(Homo sapiens (Human))
Max Institute Of Psychiatry

Curated by ChEMBL
LigandPNGBDBM50132556((S)-1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-...)
Affinity DataIC50:  8.36E+3nMAssay Description:Binding affinity to FKBP51 FK1 domain by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Max Planck Institute Of Psychiatry

Curated by ChEMBL
LigandPNGBDBM50132556((S)-1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-...)
Affinity DataIC50:  44nMAssay Description:Inhibition of binding to Phe36Val (F36V) mutant of FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP4(Homo sapiens (Human))
Max Planck Institute Of Psychiatry

Curated by ChEMBL
LigandPNGBDBM50132556((S)-1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-...)
Affinity DataIC50:  9.37E+3nMAssay Description:Binding affinity to FKBP52 FK1 domain by competitive fluorescence polarization assayMore data for this Ligand-Target Pair