BDBM50132624 (S)-3-(Formyl-hydroxy-amino)-2-isobutyl-4-methyl-pentanoic acid [(1S,2S)-2-methyl-1-(pyridin-2-ylcarbamoyl)-butyl]-amide::CHEMBL111262

SMILES CC[C@H](C)[C@H](NC(=O)C(CC(C)C)[C@H](C(C)C)N(O)C=O)C(=O)Nc1ccccn1

InChI Key InChIKey=SMZPWUUYPYYHIV-LYKJFQGKSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50132624   

TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50132624((S)-3-(Formyl-hydroxy-amino)-2-isobutyl-4-methyl-p...)
Affinity DataIC50:  19nMAssay Description:In vitro inhibition of matrix metalloprotease-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132624((S)-3-(Formyl-hydroxy-amino)-2-isobutyl-4-methyl-p...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human recombinant tumor necrosis factor-alpha converting enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50132624((S)-3-(Formyl-hydroxy-amino)-2-isobutyl-4-methyl-p...)
Affinity DataIC50:  7nMAssay Description:In vitro inhibition of matrix metalloprotease-13.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed