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BDBM50133104 8-Chloro-9-nitro-5,6-dihydro-pyrazolo[1,5-c]quinazoline-2,5-dicarboxylic acid 2-ethyl ester::CHEMBL131258

SMILES: CCOC(=O)c1cc2-c3cc(c(Cl)cc3NC(C(O)=O)n2n1)[N+]([O-])=O

InChI Key: InChIKey=YAMDMBCFVXPSBZ-UHFFFAOYSA-N

Data: 1 KI

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50133104   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutamate receptor ionotropic, NMDA 1


(RAT)
BDBM50133104
PNG
(8-Chloro-9-nitro-5,6-dihydro-pyrazolo[1,5-c]quinaz...)
Show SMILES CCOC(=O)c1cc2-c3cc(c(Cl)cc3NC(C(O)=O)n2n1)[N+]([O-])=O
Show InChI InChI=1S/C14H11ClN4O6/c1-2-25-14(22)9-5-10-6-3-11(19(23)24)7(15)4-8(6)16-12(13(20)21)18(10)17-9/h3-5,12,16H,2H2,1H3,(H,20,21)
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Similars

Article
PubMed
1.06E+4n/an/an/an/an/an/an/an/a



Moscow State University

Curated by ChEMBL


Assay Description
Binding selectivity towards N-methyl-D-aspartate glutamate receptor 1 was determined by using [3H]- glycine/NMDA


J Med Chem 46: 4063-9 (2003)


Article DOI: 10.1021/jm030833a
BindingDB Entry DOI: 10.7270/Q2445KVC
More data for this
Ligand-Target Pair