BDBM50133629 2,3-Dioxo-2,3-dihydro-indole-1-carboxylic acid benzyl ester::CHEMBL119515

SMILES O=C(OCc1ccccc1)N1C(=O)C(=O)c2ccccc12

InChI Key InChIKey=YDHPGKMAVWLLPZ-UHFFFAOYSA-N

Data  1 KI  1 IC50  2 Koff  2 Kon

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50133629   

TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50133629(2,3-Dioxo-2,3-dihydro-indole-1-carboxylic acid ben...)
Show SMILES O=C(OCc1ccccc1)N1C(=O)C(=O)c2ccccc12
Show InChI InChI=1S/C16H11NO4/c18-14-12-8-4-5-9-13(12)17(15(14)19)16(20)21-10-11-6-2-1-3-7-11/h1-9H,10H2
Affinity DataKi:  3.80E+3nMAssay Description:Inhibition constant against alpha-chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50133629(2,3-Dioxo-2,3-dihydro-indole-1-carboxylic acid ben...)
Show SMILES O=C(OCc1ccccc1)N1C(=O)C(=O)c2ccccc12
Show InChI InChI=1S/C16H11NO4/c18-14-12-8-4-5-9-13(12)17(15(14)19)16(20)21-10-11-6-2-1-3-7-11/h1-9H,10H2
Affinity DataKoff:  253s-1Assay Description:Inhibition constant of the compound against Alpha-chymotrypsin inhibitor was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50133629(2,3-Dioxo-2,3-dihydro-indole-1-carboxylic acid ben...)
Show SMILES O=C(OCc1ccccc1)N1C(=O)C(=O)c2ccccc12
Show InChI InChI=1S/C16H11NO4/c18-14-12-8-4-5-9-13(12)17(15(14)19)16(20)21-10-11-6-2-1-3-7-11/h1-9H,10H2
Affinity DataKoff:  7.60s-1Assay Description:Rate constant against Alpha-chymotrypsin from time dependent inhibition and reactivation dataMore data for this Ligand-Target Pair
In DepthDetails Article
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50133629(2,3-Dioxo-2,3-dihydro-indole-1-carboxylic acid ben...)
Show SMILES O=C(OCc1ccccc1)N1C(=O)C(=O)c2ccccc12
Show InChI InChI=1S/C16H11NO4/c18-14-12-8-4-5-9-13(12)17(15(14)19)16(20)21-10-11-6-2-1-3-7-11/h1-9H,10H2
Affinity DataKon:  0.000948M-1s-1Assay Description:Rate constant against alpha-chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCruzipain(Trypanosoma cruzi)
University of Cape Town

Curated by ChEMBL
LigandPNGBDBM50133629(2,3-Dioxo-2,3-dihydro-indole-1-carboxylic acid ben...)
Show SMILES O=C(OCc1ccccc1)N1C(=O)C(=O)c2ccccc12
Show InChI InChI=1S/C16H11NO4/c18-14-12-8-4-5-9-13(12)17(15(14)19)16(20)21-10-11-6-2-1-3-7-11/h1-9H,10H2
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory activity against T. brucei rhodensiense cysteine protease rhodesainMore data for this Ligand-Target Pair
TargetChymotrypsinogen B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50133629(2,3-Dioxo-2,3-dihydro-indole-1-carboxylic acid ben...)
Show SMILES O=C(OCc1ccccc1)N1C(=O)C(=O)c2ccccc12
Show InChI InChI=1S/C16H11NO4/c18-14-12-8-4-5-9-13(12)17(15(14)19)16(20)21-10-11-6-2-1-3-7-11/h1-9H,10H2
Affinity DataKon:  0.0000400M-1s-1Assay Description:Inhibition constant of the compound against Alpha-chymotrypsin inhibitor was determinedMore data for this Ligand-Target Pair
In DepthDetails Article