BDBM50134957 CHEMBL2370965::H-Tyr-Val-Nle-Gly-MePhe-Phe-Arg-D-Nal(2)-Asp-Arg-Phe-Gly-NH2

SMILES [#6]-[#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-c1ccc(-[#8])cc1)-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7][C@@]([#6])([#6]-c1ccccc1)[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6@H](-[#6]-c1ccc2ccccc2c1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6]-[#6](-[#7])=O

InChI Key InChIKey=ARYIUPJTXJSVAP-KZOUZSIBSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50134957   

TargetMelanocortin receptor 5(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50134957(CHEMBL2370965 | H-Tyr-Val-Nle-Gly-MePhe-Phe-Arg-D-...)
Affinity DataKi:  1.30E+3nMAssay Description:Binding affinity against human Melanocortin 5 receptor by gamma-MCH displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50134957(CHEMBL2370965 | H-Tyr-Val-Nle-Gly-MePhe-Phe-Arg-D-...)
Affinity DataKi:  1.30E+3nMAssay Description:Binding affinity against Melanocortin 4 receptor by gamma-MCH displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50134957(CHEMBL2370965 | H-Tyr-Val-Nle-Gly-MePhe-Phe-Arg-D-...)
Affinity DataKi:  1.40E+3nMAssay Description:Binding affinity against human Melanocortin 3 receptor by gamma-MCH displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50134957(CHEMBL2370965 | H-Tyr-Val-Nle-Gly-MePhe-Phe-Arg-D-...)
Affinity DataEC50:  150nMAssay Description:Intracellular cAMP accumulation in human Melanocortin 3 receptor functional assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50134957(CHEMBL2370965 | H-Tyr-Val-Nle-Gly-MePhe-Phe-Arg-D-...)
Affinity DataEC50:  210nMAssay Description:Intracellular cAMP accumulation in human Melanocortin 5 receptor functional assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50134957(CHEMBL2370965 | H-Tyr-Val-Nle-Gly-MePhe-Phe-Arg-D-...)
Affinity DataEC50:  53nMAssay Description:Intracellular cAMP accumulation in Melanocortin 4 receptor functional assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed