BDBM50135174 CHEMBL3747431
SMILES Cl.CN(C)c1ccc2nc3c(cc(=O)c(O)c3oc2c1)C(O)=O
InChI Key InChIKey=AQSOTOUQTVJNMY-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50135174
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of mouse DKK1 assessed as inhibition of DKK1-alkaline phophatase binding to LRP5 transfected in HEK293 cellsMore data for this Ligand-Target Pair
TargetLow-density lipoprotein receptor-related protein 6(Homo sapiens (Human))
Aristotle University Of Thessaloniki
Curated by ChEMBL
Aristotle University Of Thessaloniki
Curated by ChEMBL
Affinity DataIC50: 6.38E+3nMAssay Description:Binding affinity to human LRP6 expressed in HEK293 cells assessed as inhibition of DKK1/LRP6 interaction using compound pre-treated DKK1 conditioned ...More data for this Ligand-Target Pair
TargetLow-density lipoprotein receptor-related protein 6(Homo sapiens (Human))
Aristotle University Of Thessaloniki
Curated by ChEMBL
Aristotle University Of Thessaloniki
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Binding affinity to human LRP6 expressed in HEK293 cells assessed as inhibition of DKK1/LRP6 interaction using compound pre-treated DKK1 conditioned ...More data for this Ligand-Target Pair