BDBM50135615 4-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-benzoic acid 2-(2-dimethylamino-ethoxy)-ethyl ester::CHEMBL418783

SMILES CN(C)CCOCCOC(=O)c1ccc(cc1)S(=O)(=O)Nc1nnc(s1)S(N)(=O)=O

InChI Key InChIKey=AVCFYGNSQWJCRG-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50135615   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50135615(4-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-be...)
Affinity DataKi:  1.30nMAssay Description:Inhibitory activity against human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
Universit£

Curated by ChEMBL
LigandPNGBDBM50135615(4-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-be...)
Affinity DataKi:  7nMAssay Description:Inhibitory activity against Carbonic anhydrase IV isolated from bovine lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50135615(4-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-be...)
Affinity DataKi:  12nMAssay Description:Inhibitory activity against human carbonic anhydrase I (hCA I)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed