BDBM50135627 3-[3-Methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-(2E)-ylidenesulfamoyl]-benzoic acid 2-dimethylamino-ethyl ester::CHEMBL318028

SMILES CN(C)CCOC(=O)c1cccc(c1)S(=O)(=O)\N=c1\sc(nn1C)S(N)(=O)=O

InChI Key InChIKey=ZHYYNYNDPMTVTM-GHRIWEEISA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50135627   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50135627(3-[3-Methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-(2E)-...)
Affinity DataKi:  2.90nMAssay Description:Inhibitory activity against human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
Universit£

Curated by ChEMBL
LigandPNGBDBM50135627(3-[3-Methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-(2E)-...)
Affinity DataKi:  10nMAssay Description:Inhibitory activity against Carbonic anhydrase IV isolated from bovine lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50135627(3-[3-Methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-(2E)-...)
Affinity DataKi:  16nMAssay Description:Inhibitory activity against human carbonic anhydrase I (hCA I)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed