BDBM50135959 2-(4-Methoxy-phenyl)-5-trifluoromethyl-2H-pyrazole-3-carboxylic acid (2'-sulfamoyl-biphenyl-4-yl)-amide::CHEMBL149583

SMILES COc1ccc(cc1)-n1nc(cc1C(=O)Nc1ccc(cc1)-c1ccccc1S(N)(=O)=O)C(F)(F)F

InChI Key InChIKey=IKKTVWCKRXZHRN-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50135959   

TargetCoagulation factor X(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135959(2-(4-Methoxy-phenyl)-5-trifluoromethyl-2H-pyrazole...)
Affinity DataKi:  3.5nMAssay Description:Tested in vitro for inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135959(2-(4-Methoxy-phenyl)-5-trifluoromethyl-2H-pyrazole...)
Affinity DataKi: >1.50E+3nMAssay Description:Tested in vitro for inhibition of human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135959(2-(4-Methoxy-phenyl)-5-trifluoromethyl-2H-pyrazole...)
Affinity DataKi: >2.10E+4nMAssay Description:In vitro for inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed