BDBM50135965 2-(4-Methoxy-phenyl)-5-methyl-2H-pyrazole-3-carboxylic acid (3-fluoro-2'-sulfamoyl-biphenyl-4-yl)-amide::CHEMBL147132

SMILES COc1ccc(cc1)-n1nc(C)cc1C(=O)Nc1ccc(cc1F)-c1ccccc1S(N)(=O)=O

InChI Key InChIKey=JSJQUUOZSGSQMO-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50135965   

TargetCoagulation factor X(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135965(2-(4-Methoxy-phenyl)-5-methyl-2H-pyrazole-3-carbox...)
Affinity DataKi:  5.30nMAssay Description:Tested in vitro for inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135965(2-(4-Methoxy-phenyl)-5-methyl-2H-pyrazole-3-carbox...)
Affinity DataKi: >1.50E+3nMAssay Description:Tested in vitro for inhibition of human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135965(2-(4-Methoxy-phenyl)-5-methyl-2H-pyrazole-3-carbox...)
Affinity DataKi: >2.10E+4nMAssay Description:In vitro for inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed