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BDBM50136230 6-[(1E)-3-acetyl-3-methyltriaz-1-enyl]-N-(3-methylphenyl)quinazolin-4-amine::CHEMBL153577

SMILES: CN(\N=N\c1ccc2ncnc(Nc3cccc(C)c3)c2c1)C(C)=O

InChI Key: InChIKey=QERJKZGCVRVTNJ-GHVJWSGMSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50136230   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Epidermal growth factor receptor erbB1


(Mus musculus)
BDBM50136230
PNG
(6-[(1E)-3-acetyl-3-methyltriaz-1-enyl]-N-(3-methyl...)
Show SMILES CN(\N=N\c1ccc2ncnc(Nc3cccc(C)c3)c2c1)C(C)=O
Show InChI InChI=1S/C18H18N6O/c1-12-5-4-6-14(9-12)21-18-16-10-15(22-23-24(3)13(2)25)7-8-17(16)19-11-20-18/h4-11H,1-3H3,(H,19,20,21)/b23-22+
PDB
MMDB

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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 578n/an/an/an/an/an/a



McGill University Health Center/Royal Victoria Hospital

Curated by ChEMBL


Assay Description
Inhibition of epidermal growth factor receptor tyrosine kinase (EGFR TK)


J Med Chem 46: 5546-51 (2003)


Article DOI: 10.1021/jm030423m
BindingDB Entry DOI: 10.7270/Q2B857H0
More data for this
Ligand-Target Pair