BDBM501366 US11026936, Compound A2

SMILES C[C@@](O)(C(=O)N1CCC(CC1)C1(CC1)c1nnc([nH]1)-c1ccc(F)cc1)C(F)(F)F

InChI Key InChIKey=BERBLSORXBZFBK-GOSISDBHSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 501366   

LigandPNGBDBM501366(US11026936, Compound A2)
Affinity DataKd:  180nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM501366(US11026936, Compound A2)
Affinity DataIC50:  490nMAssay Description:The PDC inactivation assay is performed in Greiner 384-well microtiter plates and is used for high throughput screen. 4 μl of PDHK2 (human, rec,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent