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BDBM50137133 4,6-Bis-benzoylamino-isophthalic acid::CHEMBL156717::NS3763

SMILES: OC(=O)c1cc(C(O)=O)c(NC(=O)c2ccccc2)cc1NC(=O)c1ccccc1

InChI Key: InChIKey=UUDYZUDTQPLDDP-UHFFFAOYSA-N

Data: 6 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50137133   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
GRIK1


(Homo sapiens (Human))
BDBM50137133
PNG
(4,6-Bis-benzoylamino-isophthalic acid | CHEMBL1567...)
Show SMILES OC(=O)c1cc(C(O)=O)c(NC(=O)c2ccccc2)cc1NC(=O)c1ccccc1
Show InChI InChI=1S/C22H16N2O6/c25-19(13-7-3-1-4-8-13)23-17-12-18(16(22(29)30)11-15(17)21(27)28)24-20(26)14-9-5-2-6-10-14/h1-12H,(H,23,25)(H,24,26)(H,27,28)(H,29,30)
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Article
PubMed
1.60E+3n/an/an/an/an/an/an/an/a



NeuroSearch A/S

Curated by PDSP Ki Database




J Pharmacol Exp Ther 309: 1003-10 (2004)


Article DOI: 10.1124/jpet.103.062794
BindingDB Entry DOI: 10.7270/Q2610XX3
More data for this
Ligand-Target Pair
GRIK1


(Homo sapiens (Human))
BDBM50137133
PNG
(4,6-Bis-benzoylamino-isophthalic acid | CHEMBL1567...)
Show SMILES OC(=O)c1cc(C(O)=O)c(NC(=O)c2ccccc2)cc1NC(=O)c1ccccc1
Show InChI InChI=1S/C22H16N2O6/c25-19(13-7-3-1-4-8-13)23-17-12-18(16(22(29)30)11-15(17)21(27)28)24-20(26)14-9-5-2-6-10-14/h1-12H,(H,23,25)(H,24,26)(H,27,28)(H,29,30)
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Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



NeuroSearch A/S

Curated by PDSP Ki Database




J Pharmacol Exp Ther 309: 1003-10 (2004)


Article DOI: 10.1124/jpet.103.062794
BindingDB Entry DOI: 10.7270/Q2610XX3
More data for this
Ligand-Target Pair
GRIK1


(Homo sapiens (Human))
BDBM50137133
PNG
(4,6-Bis-benzoylamino-isophthalic acid | CHEMBL1567...)
Show SMILES OC(=O)c1cc(C(O)=O)c(NC(=O)c2ccccc2)cc1NC(=O)c1ccccc1
Show InChI InChI=1S/C22H16N2O6/c25-19(13-7-3-1-4-8-13)23-17-12-18(16(22(29)30)11-15(17)21(27)28)24-20(26)14-9-5-2-6-10-14/h1-12H,(H,23,25)(H,24,26)(H,27,28)(H,29,30)
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Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



NeuroSearch A/S

Curated by PDSP Ki Database




J Pharmacol Exp Ther 309: 1003-10 (2004)


Article DOI: 10.1124/jpet.103.062794
BindingDB Entry DOI: 10.7270/Q2610XX3
More data for this
Ligand-Target Pair
GRIK1


(Homo sapiens (Human))
BDBM50137133
PNG
(4,6-Bis-benzoylamino-isophthalic acid | CHEMBL1567...)
Show SMILES OC(=O)c1cc(C(O)=O)c(NC(=O)c2ccccc2)cc1NC(=O)c1ccccc1
Show InChI InChI=1S/C22H16N2O6/c25-19(13-7-3-1-4-8-13)23-17-12-18(16(22(29)30)11-15(17)21(27)28)24-20(26)14-9-5-2-6-10-14/h1-12H,(H,23,25)(H,24,26)(H,27,28)(H,29,30)
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Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



NeuroSearch A/S

Curated by PDSP Ki Database




J Pharmacol Exp Ther 309: 1003-10 (2004)


Article DOI: 10.1124/jpet.103.062794
BindingDB Entry DOI: 10.7270/Q2610XX3
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2


(Homo sapiens (Human))
BDBM50137133
PNG
(4,6-Bis-benzoylamino-isophthalic acid | CHEMBL1567...)
Show SMILES OC(=O)c1cc(C(O)=O)c(NC(=O)c2ccccc2)cc1NC(=O)c1ccccc1
Show InChI InChI=1S/C22H16N2O6/c25-19(13-7-3-1-4-8-13)23-17-12-18(16(22(29)30)11-15(17)21(27)28)24-20(26)14-9-5-2-6-10-14/h1-12H,(H,23,25)(H,24,26)(H,27,28)(H,29,30)
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Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



NeuroSearch A/S

Curated by PDSP Ki Database




J Pharmacol Exp Ther 309: 1003-10 (2004)


Article DOI: 10.1124/jpet.103.062794
BindingDB Entry DOI: 10.7270/Q2610XX3
More data for this
Ligand-Target Pair
GRIK1


(Homo sapiens (Human))
BDBM50137133
PNG
(4,6-Bis-benzoylamino-isophthalic acid | CHEMBL1567...)
Show SMILES OC(=O)c1cc(C(O)=O)c(NC(=O)c2ccccc2)cc1NC(=O)c1ccccc1
Show InChI InChI=1S/C22H16N2O6/c25-19(13-7-3-1-4-8-13)23-17-12-18(16(22(29)30)11-15(17)21(27)28)24-20(26)14-9-5-2-6-10-14/h1-12H,(H,23,25)(H,24,26)(H,27,28)(H,29,30)
PDB
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Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



NeuroSearch A/S

Curated by PDSP Ki Database




J Pharmacol Exp Ther 309: 1003-10 (2004)


Article DOI: 10.1124/jpet.103.062794
BindingDB Entry DOI: 10.7270/Q2610XX3
More data for this
Ligand-Target Pair
GRIK1


(Homo sapiens (Human))
BDBM50137133
PNG
(4,6-Bis-benzoylamino-isophthalic acid | CHEMBL1567...)
Show SMILES OC(=O)c1cc(C(O)=O)c(NC(=O)c2ccccc2)cc1NC(=O)c1ccccc1
Show InChI InChI=1S/C22H16N2O6/c25-19(13-7-3-1-4-8-13)23-17-12-18(16(22(29)30)11-15(17)21(27)28)24-20(26)14-9-5-2-6-10-14/h1-12H,(H,23,25)(H,24,26)(H,27,28)(H,29,30)
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Article
PubMed
n/an/a 1.60E+3n/an/an/an/an/an/a



The Danish University of Pharmaceutical Sciences

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human ionotropic glutamate receptor ionotropic kainate 1 (GluR-5) expressed in HEK293 cells.


J Med Chem 46: 5834-43 (2003)


Article DOI: 10.1021/jm030428j
BindingDB Entry DOI: 10.7270/Q2KK9B60
More data for this
Ligand-Target Pair