BDBM50137878 4-(2-Benzyloxy-phenyl)-2,4-dioxo-butyric acid::4-[2-(benzyloxy)phenyl]-2,4-dioxobutanoic acid::CHEMBL199199::CHEMBL368481::CHEMBL499444

SMILES OC(=O)C(=O)CC(=O)c1ccccc1OCc1ccccc1

InChI Key InChIKey=STKCEKDDIVPHDO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50137878   

TargetRNA-directed RNA polymerase(Hepatitis C virus)
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50137878(4-(2-Benzyloxy-phenyl)-2,4-dioxo-butyric acid | 4-...)
Affinity DataIC50:  4.40E+4nMAssay Description:Inhibitory activity against Hepatitis C virus RNA dependent RNA polymerase nonstructural protein 5BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50137878(4-(2-Benzyloxy-phenyl)-2,4-dioxo-butyric acid | 4-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of SCV helicase assessed as duplex-DNA unwinding by FRET based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50137878(4-(2-Benzyloxy-phenyl)-2,4-dioxo-butyric acid | 4-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of ATPase activity of SCV helicase assessed as phosphate release by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50137878(4-(2-Benzyloxy-phenyl)-2,4-dioxo-butyric acid | 4-...)
Affinity DataIC50:  4.40E+4nMpH: 7.5Assay Description:Inhibitory concentration against NS5B HCV polymerase using [alpha-32P]UTP as radioligand (30 degree C for 2 h, at pH 7.5 with Tris-HCl buffer)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed