BDBM50137979 7-Chloro-1-methoxymethyl-9-(4-methyl-piperazin-1-yl)-9,10-dihydro-4-thia-10a-aza-benzo[f]azulene::CHEMBL175226

SMILES COCc1ccc2Sc3ccc(Cl)cc3C(Cn12)N1CCN(C)CC1

InChI Key InChIKey=AHDOWCJMWQLFRW-UHFFFAOYSA-N

Data  4 KI

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50137979   

TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50137979(7-Chloro-1-methoxymethyl-9-(4-methyl-piperazin-1-y...)
Show SMILES COCc1ccc2Sc3ccc(Cl)cc3C(Cn12)N1CCN(C)CC1
Show InChI InChI=1S/C19H24ClN3OS/c1-21-7-9-22(10-8-21)17-12-23-15(13-24-2)4-6-19(23)25-18-5-3-14(20)11-16(17)18/h3-6,11,17H,7-10,12-13H2,1-2H3
Affinity DataKi:  316nMAssay Description:In vitro binding affinity towards Dopamine receptor D3 in Sf9 cell membranes using [3H]7-OH-DPAT as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50137979(7-Chloro-1-methoxymethyl-9-(4-methyl-piperazin-1-y...)
Show SMILES COCc1ccc2Sc3ccc(Cl)cc3C(Cn12)N1CCN(C)CC1
Show InChI InChI=1S/C19H24ClN3OS/c1-21-7-9-22(10-8-21)17-12-23-15(13-24-2)4-6-19(23)25-18-5-3-14(20)11-16(17)18/h3-6,11,17H,7-10,12-13H2,1-2H3
Affinity DataKi:  405nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 2A receptor in rat tissue homogenate using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50137979(7-Chloro-1-methoxymethyl-9-(4-methyl-piperazin-1-y...)
Show SMILES COCc1ccc2Sc3ccc(Cl)cc3C(Cn12)N1CCN(C)CC1
Show InChI InChI=1S/C19H24ClN3OS/c1-21-7-9-22(10-8-21)17-12-23-15(13-24-2)4-6-19(23)25-18-5-3-14(20)11-16(17)18/h3-6,11,17H,7-10,12-13H2,1-2H3
Affinity DataKi:  1.43E+3nMAssay Description:In vitro binding affinity towards Dopamine receptor D2 in rat tissue homogenate using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(RAT)
Universit£ degli Studi di Siena

Curated by ChEMBL
LigandPNGBDBM50137979(7-Chloro-1-methoxymethyl-9-(4-methyl-piperazin-1-y...)
Show SMILES COCc1ccc2Sc3ccc(Cl)cc3C(Cn12)N1CCN(C)CC1
Show InChI InChI=1S/C19H24ClN3OS/c1-21-7-9-22(10-8-21)17-12-23-15(13-24-2)4-6-19(23)25-18-5-3-14(20)11-16(17)18/h3-6,11,17H,7-10,12-13H2,1-2H3
Affinity DataKi: >1.00E+6nMAssay Description:In vitro binding affinity towards Dopamine receptor D1 in rat tissue homogenate using [3H]-SCH- 23390 as radioligandMore data for this Ligand-Target Pair