BDBM50138299 (S)-4-(4-Acetyl-piperazin-1-yl)-2-(4-chloro-benzyl)-1-{4-[2-(2-cyclopropyl-1-methanesulfonyl-ethyl)-phenyl]-piperazin-1-yl}-butane-1,4-dione::CHEMBL123744

SMILES CC(=O)N1CCN(CC1)C(=O)C[C@H](Cc1ccc(Cl)cc1)C(=O)N1CCN(CC1)c1ccccc1N(CC1CC1)S(C)(=O)=O

InChI Key InChIKey=YQAKIVVLZWIJRY-MHZLTWQESA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50138299   

TargetMelanocortin receptor 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50138299((S)-4-(4-Acetyl-piperazin-1-yl)-2-(4-chloro-benzyl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against human melanocortin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50138299((S)-4-(4-Acetyl-piperazin-1-yl)-2-(4-chloro-benzyl...)
Affinity DataEC50: >1.00E+4nMAssay Description:Intracellular level of cAMP in cells expressing the melanocortin 4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50138299((S)-4-(4-Acetyl-piperazin-1-yl)-2-(4-chloro-benzyl...)
Affinity DataIC50:  11nMAssay Description:Inhibitory activity against [125I]-NDP-alpha-MSH binding to the human melanocortin 4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50138299((S)-4-(4-Acetyl-piperazin-1-yl)-2-(4-chloro-benzyl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against mouse melanocortin 1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed