BDBM50138858 CHEMBL154579::[(S)-1-(4-Phenyl-1H-pyrazol-3-ylaminooxalyl)-pentyl]-carbamic acid 1-isopropyl-2-methyl-propyl ester

SMILES CCCC[C@H](NC(=O)OC(C(C)C)C(C)C)C(=O)C(=O)Nc1[nH]ncc1-c1ccccc1

InChI Key InChIKey=GCECVVNNQAGVDQ-IBGZPJMESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50138858   

TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138858(CHEMBL154579 | [(S)-1-(4-Phenyl-1H-pyrazol-3-ylami...)
Affinity DataIC50:  0.210nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138858(CHEMBL154579 | [(S)-1-(4-Phenyl-1H-pyrazol-3-ylami...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of cystiene protease cathepsin K of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed