BDBM50139403 (4-{2-[2-((R)-2-Methyl-pyrrolidin-1-yl)-ethyl]-benzofuran-5-yl}-phenyl)-morpholin-4-yl-methanone::CHEMBL422893

SMILES C[C@@H]1CCCN1CCc1cc2cc(ccc2o1)-c1ccc(cc1)C(=O)N1CCOCC1

InChI Key InChIKey=NBGOTRKECBBASK-LJQANCHMSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50139403   

TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50139403((4-{2-[2-((R)-2-Methyl-pyrrolidin-1-yl)-ethyl]-ben...)
Affinity DataKi:  0.700nMAssay Description:Binding potency was determined by displacement of [3H]-N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50139403((4-{2-[2-((R)-2-Methyl-pyrrolidin-1-yl)-ethyl]-ben...)
Affinity DataKi:  0.708nMAssay Description:Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50139403((4-{2-[2-((R)-2-Methyl-pyrrolidin-1-yl)-ethyl]-ben...)
Affinity DataKi:  1.90nMAssay Description:Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from histamine H3 receptor of rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50139403((4-{2-[2-((R)-2-Methyl-pyrrolidin-1-yl)-ethyl]-ben...)
Affinity DataKi:  2nMAssay Description:pBinding potency of the compound was determined by displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor of rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed