BDBM501398 US11026936, Compound A31

SMILES COc1ccc(cc1)-c1nnc(o1)C1(CC1)[C@H]1CCN(C[C@H]1C)C(=O)[C@@](C)(O)C(F)(F)F

InChI Key InChIKey=COCGKXQQRIKPDJ-JOTOCRJQSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 501398   

LigandPNGBDBM501398(US11026936, Compound A31)
Affinity DataKd:  3.60nMAssay Description:ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM501398(US11026936, Compound A31)
Affinity DataIC50:  180nMAssay Description:The PDC inactivation assay is performed in Greiner 384-well microtiter plates and is used for high throughput screen. 4 μl of PDHK2 (human, rec,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent