BDBM50140789 1-(2-Bromo-phenyl)-3-(4-chloro-3-cyano-2-hydroxy-phenyl)-urea::CHEMBL26830

SMILES Oc1c(NC(=O)Nc2ccccc2Br)ccc(Cl)c1C#N

InChI Key InChIKey=ARQRXWXRYLWRTM-UHFFFAOYSA-N

Data  2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50140789   

TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50140789(1-(2-Bromo-phenyl)-3-(4-chloro-3-cyano-2-hydroxy-p...)
Show SMILES Oc1c(NC(=O)Nc2ccccc2Br)ccc(Cl)c1C#N
Show InChI InChI=1S/C14H9BrClN3O2/c15-9-3-1-2-4-11(9)18-14(21)19-12-6-5-10(16)8(7-17)13(12)20/h1-6,20H,(H2,18,19,21)
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of binding of IL-8 to membranes of cloned CXC chemokine receptor 1 expressed in CHO Cells using [125I]-IL-8 radioligandMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50140789(1-(2-Bromo-phenyl)-3-(4-chloro-3-cyano-2-hydroxy-p...)
Show SMILES Oc1c(NC(=O)Nc2ccccc2Br)ccc(Cl)c1C#N
Show InChI InChI=1S/C14H9BrClN3O2/c15-9-3-1-2-4-11(9)18-14(21)19-12-6-5-10(16)8(7-17)13(12)20/h1-6,20H,(H2,18,19,21)
Affinity DataIC50: 57nMAssay Description:Inhibition of binding of IL-8 to membranes of cloned CXC chemokine receptor 2 expressed in CHO Cells using [125I]-IL-8 radioligandMore data for this Ligand-Target Pair