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BDBM50143253 CHEMBL3758256

SMILES: Cn1cc(cn1)-c1ccc(Nc2cccc(Cn3nc(ccc3=O)-c3cnn(C)c3)c2)nc1

InChI Key: InChIKey=OSQGJQQBVUJUOW-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50143253   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50143253
PNG
(CHEMBL3758256)
Show SMILES Cn1cc(cn1)-c1ccc(Nc2cccc(Cn3nc(ccc3=O)-c3cnn(C)c3)c2)nc1
Show InChI InChI=1S/C24H22N8O/c1-30-15-19(12-26-30)18-6-8-23(25-11-18)28-21-5-3-4-17(10-21)14-32-24(33)9-7-22(29-32)20-13-27-31(2)16-20/h3-13,15-16H,14H2,1-2H3,(H,25,28)
PDB
MMDB

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Similars

Article
PubMed
n/an/a>100n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


Eur J Med Chem 108: 322-33 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.042
BindingDB Entry DOI: 10.7270/Q2DJ5HG7
More data for this
Ligand-Target Pair