BDBM501437 3-methyl-1-[1-methylpropyl]-N-[(2- methyltetrazol-5-yl]methyl]-5-(2-prepoxy-3- pyridyl)pyrazolo[4,3-b]pyridin-7-amine, enantiomer 2::US11026923, Example 68

SMILES CCCOc1ncccc1C\C=C(\NCc1nnn(C)n1)c1cc(C)nn1C(C)CC

InChI Key InChIKey=GHHGVGRPPLMROZ-YBFXNURJSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 501437   

LigandPNGBDBM501437(3-methyl-1-[1-methylpropyl]-N-[(2- methyltetrazol-...)
Affinity DataIC50:  0.790nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM501437(3-methyl-1-[1-methylpropyl]-N-[(2- methyltetrazol-...)
Affinity DataIC50:  1.30nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM501437(3-methyl-1-[1-methylpropyl]-N-[(2- methyltetrazol-...)
Affinity DataIC50:  0.140nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent