BDBM501437 3-methyl-1-[1-methylpropyl]-N-[(2- methyltetrazol-5-yl]methyl]-5-(2-prepoxy-3- pyridyl)pyrazolo[4,3-b]pyridin-7-amine, enantiomer 2::US11026923, Example 68
SMILES CCCOc1ncccc1C\C=C(\NCc1nnn(C)n1)c1cc(C)nn1C(C)CC
InChI Key InChIKey=GHHGVGRPPLMROZ-YBFXNURJSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 501437
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A(Homo sapiens (Human))
H. Lundbeck
US Patent
H. Lundbeck
US Patent
Affinity DataIC50: 0.790nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...More data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C(Homo sapiens (Human))
H. Lundbeck
US Patent
H. Lundbeck
US Patent
Affinity DataIC50: 1.30nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...More data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B(Homo sapiens (Human))
H. Lundbeck
US Patent
H. Lundbeck
US Patent
Affinity DataIC50: 0.140nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...More data for this Ligand-Target Pair